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Non sedating antihistamines urticaria treatment

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This service is more advanced with JavaScript available, learn more at http: Der Hautarzt. Patienten mit chronischer spontaner Urtikaria, der häufigsten nicht akuten Verlaufsform der Nesselsucht, zeigen in der Regel einen mehrjährigen Krankheitsverlauf, eine hohe Krankheitsaktivität, eine erhebliche Beeinträchtigung der Lebensqualität und ein schlechtes Ansprechen auf Therapie. Mehr als die Hälfte der Patienten entwickelt trotz Standardtherapie mit nicht sedierenden Antihistaminika weiterhin Beschwerden. In solchen Fällen sollte das Antihistaminikum höher dosiert werden bis zur 4-fachen Tagesdosis. Wenn auch dies nicht zu einer Kontrolle der Beschwerden führt, sollte das hoch dosierte Antihistaminikum mit einem Leukotrienantagonisten kombiniert werden und ggf.
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urtikaria network e.V. | Spontaneous chronic urticaria

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Spontaneous chronic urticaria

E-mail address: Chronic urticaria is defined by the presence of pruritic wheals, angioedema or both for a period lasting more than six weeks. Based on what we know today, cutaneous mast cell degranulation in patients with chronic urticaria involves autoimmune mechanisms. Ruling out of differential diagnosesRuling out of severe inflammatory diseasesMeasurement of disease activity and control.
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Therapeutische Alternativen bei Antihistamintherapie-refraktärer Urtikaria

As soon as the symptoms of spontaneous urticaria persist for more than 6 weeks, spontaneous chronic urticaria is spoken of. Then the probability starts to decrease that the disease will disappear again in a short time. There are many underlying causes for spontaneous urticaria. In the case of severe, therapy resistant and long persisting spontaneous urticaria a thorough search into the triggers and causes is recommended.
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